Roth Family Chiropractic, 355 New Britain Rd, Berlin, Ct 06037

Authored by Dr. Pascal Sacré via GlobalResearch.ca,

It is time for anybody to come out of this negative trance, this collective hysteria, because dearth, poverty, massive unemployment will impale, mow downwards many more people than SARS-CoV-2!

Introduction: using a technique to lock down social club

All current propaganda on the COVID-19 pandemic is based on an assumption that is considered obvious, true and no longer questioned:

Positive RT-PCR exam ways beingness sick with COVID. This supposition is misleading.

Very few people, including doctors, empathize how a PCR test works.

RT-PCR waysReal Time-Polymerase ChainReaction.

In French, it ways: Réaction de Polymérisation en Chaîne en Temps Réel.

In medicine, we utilize this tool mainly to diagnose a viral infection.

Starting from a clinical situation with the presence or absenteeism of particular symptoms in a patient, we consider different diagnoses based on tests.

In the case of certain infections, particularly viral infections, we apply the RT-PCR technique to confirm a diagnostic hypothesis suggested past a clinical picture.

We practise non routinely perform RT-PCR on whatsoever patient who is overheated, cough or has an inflammatory syndrome!

Information technology is a laboratory, molecular biology technique of gene amplification because it looks for gene traces (Dna or RNA) by amplifying them.

In addition to medicine, other fields of application are genetics, research, industry and forensics.

The technique is carried out in aspecialized laboratory, it cannot be done in whatsoever laboratory, even a hospital. This entails a certain price, and a delay sometimes of several days between the sample and the result.

Today, since the emergence of the new disease chosenCOVID-xix (COronaSixrusDisease-twenty19), the RT-PCR diagnostic technique is used to define positive cases, confirmed as SARS-CoV-2 (coronavirus responsible for the new astute respiratory distress syndrome chosen COVID-xix).

These positive cases are alloyed to COVID-nineteen cases,some of whom are hospitalized or fifty-fifty admitted to intensive care units.

Official postulate of our managers: positive RT-PCR cases = COVID-19 patients.

This is the starting postulate, the premise of all official propaganda, which justifies all restrictive government measures: isolation, confinement, quarantine, mandatory masks, color codes by country and travel bans, tracking, social distances in companies, stores and even, fifty-fifty more importantly, in schools.

This misuse of RT-PCR technique is used as a relentless and intentional strategy past some governments, supported by scientific safety councils and past the dominant media,to justify excessive measures such equally the violation of a large number of ramble rights, the destruction of the economic system with the bankruptcy of entire active sectors of society, the degradation of living conditions for a large number of ordinary citizens, under the pretext of a pandemicbased on a number of positive RT-PCR tests, and not on a real number of patients.

Technical aspects: to ameliorate empathise and not be manipulated

The PCR technique was developed by pharmacistKary B. Mullis in 1986. Kary Mullis was awarded the Nobel Prize in Chemistry in 1993.

Although this is disputed, Kary Mullis himself is said to take criticized the interest ofPCR as a diagnostic tool for an infection, peculiarly a viral one.

He stated that if PCR was a good tool for research, information technology was a very bad tool in medicine, in the dispensary.

Mullis was referring to the AIDS virus (HIV retrovirus or HIV), before the COVID-19 pandemic, but this stance on the limitation of the technique in viral infections, by its creator, cannot exist dismissed out of hand; it must be taken into business relationship!

PCR was perfected in 1992.

As the analysis can be performed in real time, continuously, it becomesRT (Real-Time) – PCR, even more than efficient.

Information technology can be done from any molecule, including those of the living, the nucleic acids that make up the genes:

• DNA (deoxyribonucleic acid)

• RNA (Ribonucleic Acid)

Viruses are not considered as "living" beings, they are packets of information (Dna or RNA) forming a genome.

It is by an distension technique (multiplication) that the molecule sought is highlighted and this indicate is very important.

RT-PCR is an amplification technique.

If at that place is Dna or RNA of the desired element in a sample, information technology is non identifiable as such.

This DNA or RNA must beamplified (multiplied) a certain number of times, sometimes a very large number of times, before it tin be detected. From a minute trace, upwards to billions of copies of a specific sample can be obtained, but this does not hateful that there is all that amount in the organism being tested.

In the case of COVID-nineteen, the element sought by RT-PCR is SARS-CoV-2, an RNA virus.

There areDeoxyribonucleic acid viruses such as Herpes and Varicella viruses.

The well-nigh well knownRNA viruses, in addition to coronaviruses, are Flu, Measles, EBOLA, ZIKA viruses.

In the case of SARS-CoV-2, RNA virus, an additional specific step is required, a transcription of RNA into Deoxyribonucleic acid by means of an enzyme, Reverse Transcriptase.

This stride precedes the amplification stage.

It is not thewhole virus that is identified, but sequences of its viral genome.

This does non mean that this factor sequence, a fragment of the virus, is non specific to the virus being sought, but it is an important nuance even so:

RT-PCR does not reveal any virus, simply only parts, specific cistron sequences of the virus.

At the beginning of the year, the SARS-CoV-2 genome was sequenced.

It consists of nearly thirty,000 base pairs. The nucleic acid (DNA-RNA), the component of the genes, is a sequence of bases. In comparing, the homo genome has more than iii billion base pairs.

Teams are continuously monitoring the development of the SARS-CoV-2 viral genome as information technology evolves, through the mutations it undergoes. Today, in that location are many variants.

By taking a few specific genes from the SARS-CoV-2 genome, it is possible to initiate RT-PCR on a sample from the respiratory tract.

For COVID-19 disease, which has a nasopharyngeal (nose) and oropharyngeal (oral fissure) entry signal, the sample should exist taken from the upper respiratory tract as deeply as possible in order to avert contagion by saliva in particular.

All the people tested said that it is very painful.

The Gold Standard (preferred site for sampling) is thenasopharyngeal (nasal) approach, the near painful road.

If there is a contraindication to the nasal approach, or preferably to the individual being tested, depending on the official organs, the oropharyngeal approach (through the rima oris) is as well acceptable. The test may trigger a nausea/vomiting reflex in the individual existence tested.

Ordinarily, for the result of an RT-PCR exam to be considered reliable,distension fromiii different genes (primers) of the virus under investigation is required.

"The primers are single-stranded Dna sequences specific to the virus. They guarantee the specificity of the distension reaction. »

"The first test adult at La Charité in Berlin by Dr. Victor Corman and his assembly in January 2020 allows to highlight theRNA sequences nowadays in iii genes of the virus called Eastward, RdRp and N. To know if the sequences of these genes are present in the RNA samples collected, it is necessary to amplify the sequences of these 3 genes in order to obtain a signal sufficient for their detection and quantification. ».

The essential notion of Bicycle Time or Cycle Threshold or Ct positivity threshold [sixteen].

An RT-PCR test is negative (no traces of the desired element) or positive (presence of traces of the desired element).

Nonetheless, even if the desired element is present in a infinitesimal, negligible quantity, the principle of RT-PCR is to be able to finally highlight it by standing the amplification cycles equally much as necessary.

RT-PCR tin push up to 60 amplification cycles, or even more than!

Here is how it works:

• Cycle 1: target x 2 (2 copies)

• Cycle ii: target x 4 (iv copies)

• Cycle iii: target x 8 (8 copies)

• Cycle four: target x 16 (16 copies)

• Bicycle 5; target x 32 (32 copies)

• Etc exponentially upwardly to 40 to 60 cycles!

When we say that the Ct (Wheel Time or Wheel Threshold or RT-PCR positivity threshold) is equal to 40, it means that the laboratory has usedxl amplification cycles, i.e. obtained240 copies.

This is what underlies thesensitivity of the RT-PCR assay.

While information technology is truthful that in medicine we similar to have high specificity and sensitivity of the tests to avert false positives and fake negatives, in the example of COVID-nineteen disease, this hypersensitivity of the RT-PCR examination caused by the number of amplification cycles used has backfired.

This over-sensitivity of the RT-PCR test is deleterious and misleading!

It detaches united states of america from the medical reality which must remain based on the real clinical state of the person: is the person ill, does he or she accept symptoms?

That is the most important thing!

As I said at the beginning of the article, in medicine we always start from the person: we examine him/her, we collect his/her symptoms (complaints-anamnesis) and objective clinical signs (examination) and on the basis of a clinical reflection in which scientific knowledge and feel intervene, we brand diagnostic hypotheses.

But so do we prescribe the most appropriate tests, based on this clinical reflection.

We constantly compare the test results with the patient'sclinical condition (symptoms and signs), whichtakes precedence over everything else when it comes to our decisions and treatments.

Today, our governments, supported past their scientific safety advice, are making us practice the opposite and put the test kickoff, followed by a clinical reflection necessarily influenced past this prior test, whose weaknesses we accept just seen, peculiarly its hypersensitivity.

None of my clinical colleagues can contradict me.

Apart from very special cases such as genetic screening for sure categories of populations (age groups, sex) and certain cancers or family genetic diseases, we always piece of work in this direction: from the person (symptoms, signs) to the advisable tests, never the other mode effectually.

This is the decision of an commodity in the Swiss Medical Journal (RMS) published in 2007, written by doctors Katia Jaton and Gilbert Greub microbiologists from the University of Lausanne :

PCR in microbiology: from Dna amplification to result estimation:

"To interpret the result of a PCR, information technology is essential that clinicians and microbiologists share their experiences, so that the analytical and clinical levels of interpretation tin can exist combined."

It would be indefensible to give everyone an electrocardiogram to screen everyone who might accept a center attack one 24-hour interval.

On the other paw, in certain clinical contexts or on the footing of specific evocative symptoms, there, aye, an electrocardiogram tin be beneficial.

Dorsum toRT-PCR and Ct (Cycle Fourth dimension or Cycle Threshold).

In the case of an infectious illness, specially a viral one, the notion ofcontagiousness is another important element.

Since some scientific circles consider that an asymptomatic person can transmit the virus, they believe it is important to test for the presence of virus, even if the person is asymptomatic, thus extending the indication of RT-PCR to everyone.

Are RT-PCR tests good tests for contagiousness?

This question brings us back to the notion of viral load and thereforeCt.

The relationship between contagiousness and viral load is disputed by some people and no formal proof, to date, allows us to make a determination.

However, common sense gives obvious credence to the notion that the more virus a person has inside him or her, specially in the upper airways (oropharynx and nasopharynx), with symptoms such as coughing and sneezing,the college the risk of contagiousness, proportional to the viral load and the importance of the person'due south symptoms.

This is calledcommon sense, and although modernistic medicine has benefited greatly from the contribution of science through statistics and Testify-Based Medicine (EBM), information technology is still based primarily on common sense, experience and empiricism.

Medicine is theart of healing.

No test measures the amount of virus in the sample!

RT-PCR isqualitative: positive (presence of the virus) or negative (absenteeism of the virus).

This notion of quantity, therefore of viral load, tin be estimated indirectly by the number of amplification cycles (Ct) used to highlight the virus sought.

• The lower the Ct used to find the virus fragment, the higher the viral load is considered to be (loftier).

• The college the Ct used to detect the virus fragment, the lower the viral load is considered to be (low).

Thus, the French National Reference Centre (CNR), in the astute phase of the pandemic, estimated that the peak of viral shedding occurred at the onset of symptoms, with an amount of virus corresponding toapproximately 108 (100 million) copies of SARS-CoV-2 viral RNA on average (French COVID-xix cohort data) with a variable duration of shedding in the upper airways (from five days to more than than v weeks) [19].

This number of 108 (100 million) copies/μl corresponds to a very depression Ct.

A Ct of 32 corresponds to 10-fifteen copies/μl.

A Ct of 35 corresponds to well-nigh 1 re-create/μl.

In a higher place Ct 35, information technology becomes impossible to isolate a complete virus sequence and culture it!

In France and in most countries, Ct levels above 35, fifty-fifty twoscore, are however used even today!

The French Lodge of Microbiology (SFM) issued an stance on September 25, 2020 in which it does non recommend quantitative results, and it recommends to make positive upward to a Ct of 37 for a unmarried gene [twenty]!

With i copy/μl of a sample (Ct 35), without cough, without symptoms, one can understand why all these doctors and scientists say thata positive RT-PCR examination ways nothing, nothing at all in terms of medicine and clinic!

Positive RT-PCR tests, without whatever mention of Ct or its relation to the presence or absenteeism of symptoms, are used every bit is past our governments as the exclusive argument to employ and justify their policy of severity, austerity, isolation and aggression of our freedoms, with the impossibility to travel, to encounter, to live normally!

There is no medical justification for these decisions, for these governmental choices!

In an article published on the website of the New York Times (NYT) on Sabbatum, August 29, American experts from Harvard University are surprised that RT-PCR tests as practiced tin serve equally tests of contagiousness, even more and then every bit testify of pandemic progression in the case of SARS-CoV-ii infection [21].

According to them, the threshold (Ct) considered results in positive diagnoses in people who practise non stand for whatever take chances of transmitting the virus!

The binary "yes/no" answer is non enough, according to this epidemiologist from the Harvard University School of Public Health.

"Information technology's theamount of virus that should dictate the course of action for each patient tested. »

The amount of virus (viral load); only also and in a higher place all the clinical land, symptomatic or not of the person!

This calls into question the use of the binary result of this RT-PCR test todecide whether a person is contagious and must follow strict isolation measures.

These questions are being raised by many physicians around the world, not simply in the U.s. just also in France, Belgium (Belgium Health Experts Demand Investigation Of WHO For Faking Coronavirus Pandemic), France, Germany, Italy, the Uk, the Usa and the Great britain. in Frg, Spain…

Co-ordinate to them:

"We are going to put tens of thousands of people in confinement, in isolation, for nothing. » [22]. 22] And inflict suffering, anguish, economical and psychological dramas by the thousands!

Well-nigh RT-PCR tests fix the Ct at xl, according to the NYT. Some set it at 37.

"Tests with such high thresholds (Ct) may not only detect live virus merely also gene fragments, remnants of an sometime infection that practice not correspond any item danger," the experts said.

A virologist at the University of California admits that an RT-PCR test with a Ct greater than 35 is too sensitive. "A more reasonable threshold would be between xxx and 35," she adds.

Almost no laboratory specifies the Ct (number of amplification cycles performed) or the number of copies of viral RNA per sample μl.

Hither is an example of a laboratory result (canonical by Sciensano, the Belgian national reference center) in an RT-PCR negative patient:

No mention of Ct.

In the NYT, experts compiled three datasets with officials from the states of Massachusetts, New York and Nevada that mention them.

Conclusion?

"Upwards to 90% of the people who tested positive did not conduct a virus. »

The Wadworth Center, a New York Land laboratory, analyzed the results of its July tests at the request of the NYT: 794 positive tests with a Ct of 40.

"With aCt threshold of 35, approximatelyhalf of these PCR tests would no longer be considered positive," said the NYT.

"And nearly70% would no longer be considered positive with aCt of thirty! "

In Massachusetts,between 85 and 90% of people who tested positive in July with a Ct of forty would have been considerednegative with a Ct of 30, adds the NYT.And nevertheless, all these people had to isolate themselves, with all the dramatic psychological and economical consequences, while they were not ill and probably non contagious at all.

In France, the Heart National de Référence (CNR), the French Gild of Microbiology (SFM) continue to push Ct to 37 and recommend to laboratories to employ simply i gene of the virus as a primer.

I remind y'all that from Ct 32 onwards, it becomes very difficult to culture the virus or to extract a complete sequence, which shows the completely bogus nature of this positivity of the test, with such high Ct levels, to a higher place 30.

Similar results were reported past researchers from the Uk Public Wellness Agency in an article published on August thirteen in Eurosurveillance: "The probability of culturing the virus drops to 8% in samples with Ct levels higher up 35."

In add-on, currently, the National Reference Center in French republic just evaluates the sensitivity of commercially bachelor reagent kits, not their specificity: serious doubts persist about the possibility of cross-reactivity with viruses other than SARS-CoV-ii, such equally other benign cold coronaviruses.

It is potentially the same situation in other countries, including Kingdom of belgium.

Similarly, mutations in the virus may have invalidated certain primers (genes) used to observe SARS-CoV-2: the manufacturers give no guarantees on this, and if the AFP fast-checking journalists tell you otherwise, test their practiced faith by asking for these guarantees, these proofs.

If they have zippo to hide and if what I say is false, this guarantee will be provided to y'all and will bear witness their skilful faith.

1. We must demand that the RT-PCR results be returned mentioning theCt used because beyond Ct 30, a positive RT-PCR exam means nothing.

2. We must listen to the scientists and doctors, specialists, virologists who recommend the apply ofadapted Ct, lower, at 30. An alternative is to obtain the number of copies of viral RNA/μl or /ml sample.

3. We need tobecome back to the patient, to the person, to his or her clinical condition (presence or absence of symptoms) and from there to judge the appropriateness of testing and the best way to interpret the effect.

Until there is a better rationale for PCR screening, with a known and advisable Ct threshold, an asymptomatic person should non be tested in any way.

Even a symptomatic person should not automatically be tested, as long as they can place themselves in isolation for seven days.

Let'southward cease this debauchery of RT-PCR testing at too high Ct levels and render to clinical, quality medicine.

Once we empathise how RT-PCR testing works, information technology becomes incommunicable to let the current government routine screening strategy, inexplicably supported past the virologists in the rubber councils, continue.

My hope is that,finally, properly informed, more and more people will demand that this strategy exist stopped, considering it is all of us, aware, guided by real benevolence and common sense, who must decide our commonage and private destinies.

No i else should practice information technology for united states, especially when we realize that those who make up one's mind are no longer reasonable or rational.

Summary of important points :

• The RT-PCR exam is a laboratory diagnostic technique that is not well suited to clinical medicine.

• It is a binary, qualitative diagnostic technique that confirms (positive exam) or not (negative test) the presence of an element in the medium existence analyzed. In the instance of SARS-CoV-2, the chemical element is a fragment of the viral genome, not the virus itself.

• In medicine, fifty-fifty in an epidemic or pandemic situation, information technology is dangerous to place tests, examinations, techniques above clinical evaluation (symptoms, signs). It is the reverse that guarantees quality medicine.

• The main limitation (weakness) of the RT-PCR exam, in the current pandemic situation, is its extreme sensitivity (imitation positive) if a suitable threshold of positivity (Ct) is not called. Today, experts recommend using a maximum Ct threshold of 30.

• This Ct threshold must be informed with the positive RT-PCR consequence so that the physician knows how to interpret this positive result, particularly in an asymptomatic person, in lodge to avoid unnecessary isolation, quarantine, psychological trauma.

• In improver to mentioning the Ct used, laboratories must go along to ensure the specificity of their detection kits for SARS-CoV-ii, taking into account its most contempo mutations, and must go along to use three genes from the viral genome beingness studied equally primers or, if not, mention it.

Overall Conclusion

Is the obstinacy of governments to use the electric current disastrous strategy, systematic screening by RT-PCR, due to ignorance?

Is information technology due to stupidity?

To a kind of cognitive trap trapping their ego?

In any case, we should be able to question them, and if amidst the readers of this article there are still honest journalists, or naive politicians, or people who have the possibility to question our rulers, then do then, using these clear and scientific arguments.

Information technology is all the more incomprehensible that our rulers have surrounded themselves with some of the most experienced specialists in these matters.

If I have been able to get together this information myself, shared, I remind y'all, by competent people higher up all suspicion of conspiracy, such equally Hélène Banoun, Pierre Sonigo, Jean-François Toussaint, Christophe De Brouwer, whose intelligence, intellectual honesty and legitimacy cannot be questioned, then the Belgian, French and Quebec scientific advisors, etc., know all this as well.

Then?

What's going on?

Why continue in this distorted direction, obstinately making mistakes?

It is not insignificant to reimpose confinements, curfews, quarantines, reduced social bubbles, to shake up again our shaky economies, to plunge unabridged families into precariousness, to sow so much fearfulness and anxiety generating a existent country of mail service-traumatic stress worldwide, to reduce access to care for other pathologies that nevertheless reduce life expectancy much more than COVID-xix!

Is there intent to damage?

Is in that location an intention to use the alibi of a pandemic to move humanity towards an result it would otherwise never have accustomed? In any example, non like that!

Would this hypothesis, which modernistic censors will hasten to characterization "conspiracy", be the most valid explanation for all this?

Indeed, if we draw a directly line from the present events, if they are maintained, we could find ourselves once again bars with hundreds, thousands of human beings forced to remain inactive, which, for the professions of catering, entertainment, sales, fairgrounds, itinerants, canvassers, risks being catastrophic with bankruptcies, unemployment, low, suicides by the hundreds of thousands.

The touch on education, on our children, on instruction, on medicine with long planned care, operations, treatments to be cancelled, postponed, will be profound and destructive.

"We risk a looming nutrient crisis if action is non taken quickly."

It is time for everyone to come out of this negative trance, this collective hysteria, considering famine, poverty, massive unemployment will kill, mow downwardly many more people than SARS-CoV-2!

Does all this brand sense in the face of a disease that is declining, over-diagnosed and misinterpreted past this misuse of overly sensitively calibrated PCR tests?

For many, the continuous wearing of the mask seems to accept become a new norm.

Even if information technology is constantly downplayed by some health professionals and fact-checking journalists, other doctors warn of the harmful consequences, both medical and psychological, of this hygienic obsession which, maintained permanently, is in fact an abnormality!

What a hindrance to social relations, which are the truthful foundation of a physically and psychologically healthy humanity!

Some cartel to observe all this normal, or a lesser toll to pay in the face of the pandemic of positive PCR tests.

Isolation, distancing, masking of the face, impoverishment of emotional communication, fear of touching and kissing even inside families, communities, between relatives…

Spontaneous gestures of daily life hindered and replaced by mechanical and controlled gestures …

Terrified children, kept in permanent fear and guilt…

All this will accept a deep, lasting and negative affect on homo organisms, in their concrete, mental, emotional and representation of the world and society.

This is not normal!

We cannot let our rulers, for whatever reason, organize our commonage suicide any longer.

Translated from French past Global Research. Original source: Mondialisation.ca

Dr Pascal Sacré is a medico specialized in critical care, writer and renowned public wellness analyst, Charleroi, Kingdom of belgium. He is a Enquiry Associate of the  entre for Research on Globalization (CRG)

*  *  *

Professionals whose references and comments are the ground of this article in its scientific attribute (peculiarly and mainly on RT-PCR):

i) Hélène Banoun

https://www.researchgate.internet/contour/Helene_Banoun

PhD, Pharmacist biologist

Quondam INSERM Research Officer

Former intern at the Paris Hospitals

2) Pierre Sonigo

Virologist

Research Director INSERM, worked at the Pasteur Constitute

Heads the Virus Genetics Laboratory in Cochin, Paris.

Participated in 1985 in the sequencing of the AIDS virus.

3) Christophe De Brouwer

PhD in Public Health Science

Honorary Professor at the School of Public Wellness at ULB, Belgium

4) Jean-François Toussaint

Physician, Professor of Physiology at the University of Paris-Descartes

Director of IRMES, Plant for BioMedical Research and Sports Epidemiology

Old fellow member of the Loftier Council of Public Health

englishhavermed.blogspot.com

Source: https://www.zerohedge.com/medical/covid-19-rt-pcr-test-how-mislead-all-humanity-accepting-societal-lock-downs

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